This study examines how orbital debris may affect the efficacy of space architectures over the next decade. Parametrical modeling in two dimensions is performed to examine sensitivities related to space architectures under the influence of the growing space debris hazard. The two dimensions include (1) three debris environment scenarios and (2) three low Earth orbit (LEO) space architecture options. Results highlight the possibility that spaceflight safety can be enhanced by anticipating and leveraging space system design trends and knowledge of debris hazard evolution uncertainties. There is neither a sure fire way to prevent debris from impacting LEO constellations but also no certainty that current practices will lead to failures over the next decade. However, actions taken now will have long-lasting impact on future deployments.